How to say that's impossible in Japanese

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Example Sentences

The scientific truth of evolution is so overwhelmingly established, that it is virtually impossible to refute.
"Do I really have that good a personality?" "Impossible. After all, there's this time as well, but in middle school you sold off girl's pants all over to bring in the money."
She wished for a more relaxing life, but that was impossible under the circumstances.
It's impossible that she knew about it.
It is impossible that she should have killed herself.

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